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Pediatrics Portal: Critical Appraisal

Critical Appraisal Worksheets [click files to download - IM Journal Club uses blue McMaster sheets]

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Types of Questions & study design

DETERMINING THE BEST STUDY TO SEARCH FOR DURING YOUR LITERATURE SEARCH.
Type of Question Description (What is it?) Study Design (when SR not available)
Diagnosis

An evaluation of a test, screening or other assessment such as history or physical exam

Prospective, blind comparison to a gold standard.

RCT > controlled clinical trial (CCT) > cohort > case control > case series

Therapy

An evaluation of a therapeutic or preventive intervention

RCT > CCT > cohort >case control > case series

Prognosis An evaluation of clinical outcomes over time cohort > case control > case series
Etiology/Harm

An evaluation of a therapeutic, preventive, screening or diagnostic intervention, or a non-therapeutic exposure or behavior

cohort > case control > case series

Prevention

An evaluation of the effectiveness of an intervention or exposure in preventing morbidity and mortality

RCT > CCT > cohort > case control > case series
Cost

An evaluation of cost versus benefit of a treatment or procedures

Economic analysis, cost-benefit analysis

 

JAMAevidence

JAMAevidence

Helps decision makers identify the best available evidence by providing guides to the systematic consideration of the validity, importance, and applicability of claims about the assessment of health problems and the outcomes of health care.

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